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- 产品名称:重组人Aldo-keto Reductase 1C4/AKR1C4Protein(N-6His)
- 产品型号:PN100041-10ug
- 产品展商:PERFEMIKER
- 产品价格:1200.00 元
- 产品文档:无相关文档
简单介绍
重组人Aldo-keto Reductase 1C4/AKR1C4Protein(N-6His)
货号:PN100041
规格:10ug;
标签:N-6His;
来源:Human;
表达宿主:E.coli
产品描述
名称:重组人Aldo-keto Reductase 1C4/AKR1C4Protein(N-6His);
产品说明(Description)
Recombinant Human Aldo-Keto Reductase Family 1 Member C4 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed with a 6His tag at the N-terminus.
Accession #: P17516
Known as: Aldo-Keto Reductase Family 1 Member C4; 3-Alpha-HSD1; 3-Alpha-Hydroxysteroid Dehydrogenase Type I; Chlordecone Reductase; CDR; Dihydrodiol Dehydrogenase 4; DD-4; DD4; HAKRA; AKR1C4; CHDR
制剂(Formulation)
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
质量控制(Quality Control)
Purity: Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
复溶(Reconstitution)
保存(Storage)
Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
背景(Background)
Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.
电泳(SDS-PAGE)
FOR RESEARCH USE ONLY