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  • 产品名称:3 - 氟 - 4 - 甲氧基苯甲酸

  • 产品型号:403-20-3
  • 产品厂商:Ossila
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  • 产品文档: MSDS 3-fluoro-4-methoxybenzoic-acid
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3-Fluoro-4-methoxybenzoic acid (CAS number 403-20-3) is a fluorinated para-anisic acid derivative. The fluoride substituent enables nucleophilic aromatic substitution, while most of the reactivity centered on the carboxylic group. 3-Fluoro-4-methoxybenzoic acid can undergo various reactions, including Fischer esterification affording esters with ligustrazine moiety for the treatment of Alzheimer's disease.

Furthermore, 3-Fluoro-4-methoxybenzoic acid can be transformed into benzoyl chloride using thionyl chloride to enhance its reactivity, thereby providing a platform for Friedel-Craft acylation reaction. Additionally, 3-Fluoro-4-methoxybenzoic acid can be modified into hydrazide which is used in the synthesis of oxadiazoles for antimicrobial applications.

General Information


CAS Number 403-20-3
Chemical Formula C8H7FO3
Full Name 3-Fluoro-4-methoxybenzoic acid
Molecular Weight 170.14 g/mol
Synonyms 3-Fluoro-p-anisic Acid
Classification / Family Fluorinated building blocks, Benzoic acid building blocks, Anisic acid building blocks, APIs

Chemical Structure


3-Fluoro-4-methoxybenzoic acid chemical structure, CAS 403-20-3.
3-Fluoro-4-methoxybenzoic acid chemical structure, CAS 403-20-3

Product Details


Purity 98%
Melting Point Tm = 211 °C – 213 °C
Appearance White powder
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3 - 氟 - 4 - 甲氧基苯甲酸 403-20-3
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