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产品名称：2-Fluoro-4-(trifluoromethyl)benzoic acid
- 产品型号：115029-24-8
- 产品厂商：Ossila
- 产品价格：0
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- 产品文档：
MSDS 2-fluoro-4-trifluoromethylbenzoic-acid
2-Fluoro-4-(trifluoromethyl)benzoic acid (CAS number 115029-24-8) is a benzoic acid derivative featuring a fluoride and a trifluoromethyl substituents at 2- and 4-positions. As a synthetic building block, 2-fluoro-4-(trifluoromethyl)benzoic acid can be easily attached to molecular scaffolds through condensation reactions. A structure-activity relationship study has indicated that the trifluoromethyl and fluoride group introduced by 2-fluoro-4-(trifluoromethyl)benzoic acid improve the agonistic activity of G protein-coupled receptors. The increased potency results from the halogen bonding interaction of the fluorinated groups and proteins.
2-Fluoro-4-(trifluoromethyl)benzoic acid can also undergo functional group exchanges to afford acyl chlorides, aldehydes and anhydrides.
General Information
| CAS Number | 115029-24-8 |
| Chemical Formula | C8H4F4O2 |
| Full Name | 2-Fluoro-4-(trifluoromethyl)benzoic acid |
| Molecular Weight | 208.11 g/mol |
| Synonyms | α,α,α,2-Tetrafluoro-p-toluic acid |
| Classification / Family | Fluorinated building blocks, Benzoic acid building blocks, APIs |
Chemical Structure
Product Details
| Purity | 98% |
| Melting Point | Tm = 168 °C – 170 °C |
| Appearance | White powder |