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  • 产品名称:3 - 氟对甲氧基苯胺

  • 产品型号:366-99-4
  • 产品厂商:Ossila
  • 产品价格:0
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  • 产品文档: MSDS 3-fluoro-p-anisidine
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3-Fluoro-p-anisidine (CAS number 366-99-4), also referred to as 3-fluoro-4-methoxyaniline, is an aniline with a fluoride and a methoxy substituted at 3- and 4-positions. 3-Fluoro-p-anisidine is commonly used as a precursor for synthesizing quinoline derivatives through Combes quinoline synthesis with 1,3-diketones. The as synthesized quinoline derivatives are employed as active pharmaceutical ingredients and dyes. 3-Fluoro-p-anisidine is readily attached to molecular scaffolds through nucleophilic substitution.

The primary amine in 3-fluoro-p-anisidine can be used to prepare azides for copper-catalyzed azide-alkyne cycloaddition (click reaction).

General Information


CAS Number 366-99-4
Chemical Formula C7H8FNO
Full Name 3-Fluoro-4-methoxyaniline
Molecular Weight 141.15 g/mol
Synonyms 4-Amino-2-fluoroanisole, 3-Fluoro-4-methoxyaniline, 4-Amino-2-fluoro-1-methoxybenzene
Classification / Family Fluorinated building blocks, Aniline building blocks, APIs, Heterocycles

Chemical Structure


3-Fluoro-p-anisidine chemical structure, CAS 366-99-4.
3-Fluoro-p-anisidine chemical structure, CAS 366-99-4

Product Details


Purity 97%
Melting Point Tm = 81 °C – 83 °C
Appearance Brown powder
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