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  • 产品名称:3'- 氟 - 4'- 甲氧基苯乙酮

  • 产品型号: 455-91-4
  • 产品厂商:Ossila
  • 产品价格:0
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  • 产品文档: MSDS 3-fluoro-4-methoxyacetophenone
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3′-Fluoro-4′-methoxyacetophenone (CAS number 455-91-4) is an acetophenone derivative with a fluorine and a methoxy substituents. 3′-Fluoro-4′-methoxyacetophenone is used to prepare chalcone derivatives with benzaldehydes by aldol condensation. Chalcones are α,β-unsaturated ketones employed as active pharmaceutical ingredients (APIs) and fluorescent dyes. Pyrazole derivatives such as celecoxib, an anti-inflammatory drug, are obtained from chalcones reacting with hydrazine derivatives. Chalcone derivatives can be further functionalized to produce epoxides via Juliá–Colonna epoxidation.

3′-Fluoro-4′-methoxyacetophenone is also a key component in Mannich reaction along with formaldehyde and secondary amines, for β-amino-carbonyl compounds, also known as Mannich bases.


General Information


CAS Number 455-91-4
Chemical Formula C9H9FO2
Full Name 1-(3-fluoro-4-methoxyphenyl)ethan-1-one
Molecular Weight 168.17 g/mol
Synonyms 1-(3-Fluoro-4-methoxyphenyl)-1-ethanone
Classification / Family Fluorinated building blocks, Acetophenone building blocks, Heterocycles, APIs

Chemical Structure


3′-Fluoro-4′-methoxyacetophenone chemical structure, CAS 455-91-4.
3′-Fluoro-4′-methoxyacetophenone chemical structure, CAS 455-91-4

Product Details


Purity 98%
Melting Point Tm = 92 °C – 94 °C
Appearance Off-white powder
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