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产品名称：3 - 氟 - 4 - 羟基苯甲醛
- 产品型号： 405-05-0
- 产品厂商：Ossila
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- 产品文档：
MSDS 3-fluoro-4-hydroxybenzaldehyde
3-Fluoro-4-hydroxybenzaldehyde (CAS number 405-05-0) is a fluorinated benzaldehyde bearing a fluorine and a hydroxy at 3- and 4-positions. 3-Fluoro-4-hydroxybenzaldehyde is used to synthesize analogs of curcuminoid with ketones through aldol condensation. The as synthesized curcuminoid derivatives show half maximal inhibitory concentration of 0.75 μM against human ovarian cancer cell line A2780. Hydrazone derivatives can be obtained from 3-fluoro-4-hydroxybenzaldehyde with a phenylhydrazine derivatives via aldehyde-amine condensation, showing potent inhibitory of macrophage migration in anti-inflammatory activity.
3-Fluoro-4-hydroxybenzaldehyde is also exploited to synthesize caffeic acid phenylethyl amide derivatives through Wittig reaction for cytoprotective activity against peroxides.
General Information
| CAS Number | 405-05-0 |
| Chemical Formula | C7H5FO2 |
| Full Name | 3-Fluoro-4-hydroxybenzaldehyde |
| Molecular Weight | 140.11 g/mol |
| Synonyms | 2-Fluoro-4-formylphenol |
| Classification / Family | Fluorinated building blocks, Benzaldehyde building blocks, APIs |
Chemical Structure
Product Details
| Purity | 97% |
| Melting Point | Tm = 121 °C – 124 °C |
| Appearance | Beige powder |