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6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride (CAS number 84163-13-3), a fluorinated heterocycle compound, contains a benzisoxazole (a benzene-fused isoxazole), a piperidine and a fluorine substituent. 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride is primarily involved in the synthesis of atypical antipsychotics such as risperidone, paliperidone and iloperidone for the treatment of schizophrenia. 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride is also exploited as a molecular scaffold for antimicrobials, antidepressants and anticancer drugs.

6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride can be easily modified via acylation and sulfonylation with acyl chloride or sulfonyl chloride. It also reacts with alkyl chloride/bromide to form N-alkylated products.
General Information
| CAS Number | 84163-13-3 |
| Chemical Formula | C12H14ClFN2O |
| Full Name | 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride |
| Molecular Weight | 256.70 g/mol |
| Synonyms | R-56109 hydrochloride, 4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidine hydrochloride, 6-fluoro-3-(piperidin-4-yl)benzo[d]isoxazole hydrochloride |
| Classification / Family | Fluorinated building blocks, Heterocyclic building blocks, APIs, Drug discovery |
Chemical Structure

Product Details
| Purity | 98% |
| Melting Point | N/A |
| Appearance | White powder |
