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Ethyl (4-fluorobenzoyl)acetate (p-EFBA), CAS number 1999-00-4, the analog of β-Ketoester, is typically used as a ligand for improving stereoselectivity of catalytic reactions for great chelating ability to metal centers. Ethyl (4-fluorobenzoyl)acetate is an ideal starting material for synthesizing pyrimidine derivatives via Pinner pyrimidine reaction with amidine/guanidine. The iridium complexes formed by those pyrimidine derivatives are used for long lasting blue phosphorescent organic light-emitting diodes (PhOLEDs). The self-assembled monomer layer of pyrimidine derivatives can engineer the interfacial band of MoS2 and gold for enhanced device performance in thin film transistors.
Ethyl (4-fluorobenzoyl)acetate can be obtained by the reaction of 4-fluoroacetophenone with diethyl carbonate and sodium hydride as the base in great yield.
General Information
| CAS Number | 1999-00-4 |
| Chemical Formula | C11H11FO3 |
| Full Name | Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate |
| Molecular Weight | 210.20 g/mol |
| Synonyms | (4-Fluorobenzoyl)acetic acid ethyl ester, 3-(4-Fluorophenyl)-3-oxopropionic acid ethyl ester |
| Classification / Family | Ketoester derivatives, Fluorinated building blocks, Semiconductor synthesis intermediates, Dyes |
| Purity | >97% |
| Boiling Point | Tb = 355 °C – 360 °C at 760 mmHg |
| Relative Density |
1.174 g/mL at 25 °C |
| Appearance | Slightly yellow liquid |
