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产品名称：5-(三氟甲氧基) 靛红
- 产品型号：169037-23-4
- 产品厂商：Ossila
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- 产品文档：
5-trifluoromethoxyisatin
5-(Trifluoromethoxy)isatin (CAS number 169037-23-4), a derivative of indole, has two carbonyls at 2,3-position and a trifluoromethoxy at 5-position. In 5-(trifluoromethoxy)isatin, the carbonyl at 3-position is more reactive than the amide carbonyl at 2-position, thus it is readily functionalized under nucleophilic substitution. The nucleophilic substitution can also be enantioselective with the addition of chiral catalysts, with up to 92% ee (enantiomeric excess).
5-(Trifluoromethoxy)isatin is used to synthesize luminescent gold(I) complexes, displaying an emission at 400 nm. The isatin-gold complexes show cytotoxicity to cancer cells with half-maximal inhibitory concentration (IC50) as low as 0.28 μM. 5-(Trifluoromethoxy)isatin is also used to modify rhodamine in application of selectively detection of Cr3+. An isatin decorated fullerene (C60) has improved miscibility to P3HT in heterojunction organic solar cells.
General Information
| CAS Number | 169037-23-4 |
| Chemical Formula | C9H4F3NO3 |
| Full Name | 5-(Trifluoromethoxy)-1H-indole-2,3-dione |
| Molecular Weight | 231.13 g/mol |
| Synonyms | 5-(Trifluoromethoxy)-2,3-indolinedione |
| Classification / Family | Fluorinated building blocks, Heterocyclic building blocks, Solar cells, OLEDs |
Chemical Structure
Product Details
| Purity | 98% |
| Melting Point | Tm = 170 °C – 172 °C |
| Appearance | Orange to brown powder |