产品名称：1-[2-(Trifluoromethyl)phenyl]imidazole

1-[2-(Trifluoromethyl)phenyl]imidazole (CAS number 25371-96-4) is a trifluoromethyl substituted benzene ring connecting to an imidazole at ortho-position. By having a carbon-carbon single bond connected benzene and imidazole, 1-[2-(Trifluoromethyl)phenyl]imidazole shows strong binding affinity to transition metals such as iridium (Ir) and ruthenium (Ru). The homoleptic iridium(III)-phenylimidazole complexes show high photoluminescence quantum yields (53%) and in OLED devices they display high current efficiency of 20 cd/A at luminance of 1000 cd/m2. A cyclometalated ruthenium complex with phenylimidazole is used as a chromogenic sensor for detecting fluoride in acetonitrile, showing a red shift from 565 nm to 618 nm (solution color changed from red to green).

1-[2-(Trifluoromethyl)phenyl]imidazole has been vastly investigated as an inhibitor of neuronal nitric oxide synthase which is involved in depression and anxiety. 1-[2-(trifluoromethyl)phenyl]imidazole (30 mg/kg/day) shows significant antidepressant-like effect in vitro and in vivo study.

Multiple functional groups

For facile synthesis

Fluorinated imidazole building block

For drug discovery, biochemistry, and OLEDs

Worldwide shipping

Quick and reliable shipping

High purity

>98% High purity

General Information

Chemical Structure

Product Details