产品名称：6 - 氟吲哚 - 2 - 羧酸

6-Fluoroindole-2-carboxylic acid (CAS number 3093-97-8) is a fluorinated indole derivative, having a fluorine at 6-position and a carboxylic acid at 2-position. The secondary amine and carboxylic acid in 6-Fluoroindole-2-carboxylic acid form an α-amino acid moiety. This allows 6-fluoroindole-2-carboxylic acid to have a zwitterionic form where the proton of the carboxylic acid is transferred to the amine. In fluorescence spectra, the neutral form and zwitterionic form of 6-fluoroindole-2-carboxylic acid have different emission band at 332 and 370 nm respectively, forming a broad fluorescence emission peak.

The carboxylic acid group in 6-fluoroindole-2-carboxylic acid can bind to copper(II), yielding a binuclear complex. The complex shows anti-cancer activity towards breast cancer cell lines (MDA-MB-231 and MCF-7) with percentage of inhibition of 90% at 20 µM concentration.

6-Fluoroindole-2-carboxylic acid can be used to synthesize triindoles, via a palladium catalyzed decarboxylative reaction. Triindoles are used as semiconductors in OFETs with field effect mobility of 0.03 cm2V-1S-1, as well as hole transport layers in solar cells.

Multiple functional groups

For facile synthesis

Fluorinated indole building block

For drug discovery, solar cells, and OLEDs

Worldwide shipping

Quick and reliable shipping

High purity

>98% High purity

General Information

Chemical Structure

Product Details