人心肌细胞 HCM

心肌细胞是机体*具有活力的细胞。它们是高度分化的高氧含量的细胞，拥有大量的线粒体。心肌细胞占有心脏重量的75%，但仅为心脏细胞数量的1/3。高度分化的心肌细胞几乎没有增殖能力，它们在a-肾上腺素的刺激下通过Ras/MEK途径发生肥大生长。所有的心肌细胞都能自律性的将膜去极化和复极化。所有的心肌细胞收缩都是肌源性的，不受神经系统刺激。心肌细胞具有复杂的信号网络，从而调节其在心脏节律性的泵出功能中的作用。心力衰竭时，心肌细胞的肥大和凋亡导致心肌收缩功能的下降。更好地了解心脏信号系统有助于揭示心肌细胞死亡的细胞机制。
Sciencell研究实验室的HCM是从人心脏分离得到的，原代冻存，冰冻运输。每管细胞密度超过1×10^6/ml。细胞特性经肌球蛋白（myosin）免疫荧光鉴定。本细胞经检测不含HIV-1、HBV、HCV、支原体、细菌、酵母菌和真菌。如采用ScienCell?实验室提供的培养条件，可保证此细胞继续的培养。HCM因为不能增殖，故不能够扩大或长期培养。?

推荐培养基：心肌细胞培养基 (CMM, Cat. #6201)

货号	6200
产地	美国
缩写	HCM
规格	1 x 10^6 /1ml
用途	科研
储存	液氮
运输	干冰
关键字	人心肌细胞 HCM  人心肌细胞 HCM  人心肌细胞 HCM  人心肌细胞 HCM  人心肌细胞 HCM  人心肌细胞 HCM  人心肌细胞 HCM
公司简介	合肥星肽生物科技有限公司作为专业的ScienCell中国代理商，专业经营实验室科研用原代细胞、原代细胞专用培养基、原代细胞无血清培养基、干细胞、干细胞培养基、干细胞无血清培养基的研究和开发。合肥星肽生物科技有限公司始终致力于为客户提供可靠的研究材料以及方便快捷的服务，对购买项目的前期资料提供,中期合同保证,后期货物跟踪到 *终售后的确保项目准确到位，都有相关专业人士进行维护,确保您在合肥合肥星肽生物科技有限公司公司获得***服务！
联系方式	何经理，合肥星肽生物科技有限公司，Tel：      ************，                                                  E-mail：info@qingbio.com      http://www.qingbio.com      QQ:514713116

1.) Wang E, Sun S, Qiao B, Duan W, Huang G, An Y, Xu S, Zheng Y, Su Z, Gu X, Jin L, Wang H. (2013) "Identification of functional mutations in GATA4 in patients with congenital heart disease." PLoS One. 8: e62138.

2.) Bauwens CL, Song H, Thavandiran N, Ungrin M, Mass? S, Nanthakumar K, Seguin C, Zandstra PW. (2011) "Geometric Control of Cardiomyogenic Induction in Human Pluripotent Stem Cells." Tissue Eng Part A. 17: 1901-9.

3.) Mukhopadhyay P, Rajesh M, B?tkai S, Patel V, Kashiwaya Y, Liaudet L, Evgenov OV, Mackie K, Hask? G, Pacher P. (2010) "CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes." Cardiovasc Res. 85: 773-84.

4.) Voigt A, Trimpert C, Bartel K, Egerer K, Kuckelkorn U, Feist E, Gericke C, Klingel K, Kandolf R, Felix SB, Baumann G, Kloetzel PM, Stangl K, Staudt A. (2010) "Lack of evidence for a pathogenic role of proteasome-directed autoimmunity in dilated cardiomyopathy." Basic Res Cardiol. 105: 557-67.

5.) Yeh YC, Wei HJ, Lee WY, Yu CL, Chang Y, Hsu LW, Chung MF, Tsai MS, Hwang SM, Sung HW. (2010) "Cellular cardiomyoplasty with human amniotic fluid stem cells: in vitro and in vivo studies." Tissue Eng Part A. 16: 1925-36.

6.) Hussein S, Michael P, Brabant D, Omri A, Narain R, Passi K, Ramana CV, Parrillo JE, Kumar A, Parissenti A, Kumar A. (2009) "Characterization of human septic sera induced gene expression modulation in human myocytes." Int J Clin Exp Med. 2: 131-48.

7.) Kim KS, Chapman NM, Tracy S. (2008) "Replication of coxsackievirus B3 in primary cell cultures generates novel viral genome deletions." J Virol. 82: 2033-7.

8.) Pan CH, Wen CH, Lin CS. (2008) "Interplay of angiotensin II and angiotensin(1-7) in the regulation of matrix metalloproteinases of human cardiocytes." Exp Physiol. 93: 599-612.

9.) Jiang Y, Reynolds C, Xiao C, Feng W, Zhou Z, Rodriguez W, Tyagi SC, Eaton JW, Saari JT, Kang YJ. (2007) "Dietary copper supplementation reverses hypertrophic cardiomyopathy induced by chronic pressure overload in mice." J Exp Med. 204: 657-66.

10.) Li SY, Sigmon VK, Babcock SA, Ren J. (2007) "Advanced glycation endproduct induces ROS accumulation, apoptosis, MAP kinase activation and nuclear O-GlcNAcylation in human cardiac myocytes." Life Sci. 80: 1051-6.

11.) Ng ES, Cheng ZJ, Ellis A, Ding H, Jiang Y, Li Y, Hollenberg MD, Triggle CR. (2007) "Nitrosothiol stores in vascular tissue: Modulation by ultraviolet light, acetylcholine and ionomycin." Eur J Pharmacol. 560: 183-92.

12.) Spector NL, Yarden Y, Smith B, Lyass L, Trusk P, Pry K, Hill JE, Xia W, Seger R, Bacus SS. (2007) "Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells." Proc Natl Acad Sci USA. 104: 10607-12.

13.) Li SY, Li Q, Shen JJ, Dong F, Sigmon VK, Liu Y, Ren J. (2006) "Attenuation of acetaldehyde-induced cell injury by overexpression of aldehyde dehydrogenase-2 (ALDH2) transgene in human cardiac myocytes: role of MAP kinase signaling." J Mol Cell Cardiol. 40: 283-94.
?

There are no product questions yet.