产品详情
  • 产品名称:MicroVue Factor H EIA

  • 产品型号:A039
  • 产品厂商:Quidel Corporation
  • 产品价格:0
  • 折扣价格:0
  • 产品文档:
你添加了1件商品 查看购物车
简单介绍:
The alternative complement pathway provides innate protection against microbial agents in the absence of specific antibody.1-5 The activation of this complement pathway can be triggered by a variety of substances including microbial polysaccharides or lipids, gram negative bacterial lipopolysaccharides, and surface determinants present on some viruses, parasites, virally infected mammalian cells,
详情介绍:

For Research Use Only. Not for use in diagnostic procedures.

The alternative complement pathway provides innate protection against microbial agents in the absence of specific antibody.1-5 The activation of this complement pathway can be triggered by a variety of substances including microbial polysaccharides or lipids, gram negative bacterial lipopolysaccharides, and surface determinants present on some viruses, parasites, virally infected mammalian cells, and cancer cells. In autoimmune diseases, the alternative complement pathway may contribute directly to tissue damage.

Factor H is involved in the regulation of the alternative pathway of complement. In blood, activation of C3, under normal conditions, is kept at a low level by the control proteins, Factor H and Factor I. Factor H functions in two ways to inactivate the C3bBb enzyme: (1) it accelerates the dissociation of Bb from C3b; and (2) it serves as a cofactor for Factor I, a serine protease, which cleaves C3b into iC3b, which can no longer form the C3 convertase with Factor B.6

References: 
  1. Pangburn, M.K. and Müller-Eberhard, H.J. The alternative pathway of complement. Springer Semin. Immunopathol. 1984;7:163.

  2. Ratnoff, W.E., Fearon, D.T., and Austen, K.F. The role of antibody in the activation of the alternative complement pathway. Springer Semin. Immunopathol. 1983;6:361.

Product Specifications

Format

ELISA

Assay time

150 minutes

Test/kit

96 wells/plate

Sample Type

Various

Ordering Information

Catalog Number Description
A039

96 Wells/Plate, control included

A040

96 Wells/Plate, control included

标题:
内容:
联系人:
联系电话:
Email:
公司名称:
联系地址:
 
 
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
相关文章

沪公网安备 31011202007343号