产品详情
简单介绍：
Ciliary Neurotrophic Factor (CNTF) Antibody
详情介绍：
CNTF Antibody is a Rabbit Polyclonal antibody against CNTF. The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
| Target | CNTF |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Tested Applications | WB |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen | Recombinant protein of human CNTF. |
| Purification | Affinity purified. |
| Form | Liquid |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight | Calculated MW: 22 kDa Observed MW: 26 kDa |
| Swiss Prot | P26441 |
| GeneID | 1270 |
| Gene Symbol | CNTF |
| Concentration | > 1 mg/ml |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code | 12352203 |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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