产品详情
简单介绍：
14-3-3 Protein Epsilon (YWHAE) Antibody
详情介绍：
YWHAE Antibody is a Rabbit Polyclonal antibody against YWHAE. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
| Target | YWHAE |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Tested Applications | WB |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen | Recombinant protein of human YWHAE. |
| Purification | Affinity purified. |
| Form | Liquid |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight | Calculated MW: 26 kDa/29 kDa Observed MW: 29 kDa |
| Swiss Prot | P62258 |
| GeneID | 7531 |
| Gene Symbol | YWHAE |
| Concentration | > 1 mg/ml |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code | 12352203 |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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