For Research Use Only. Not for use in diagnostic procedures.
The MicroVue Factor I Enzyme Immunoassay (EIA) measures the amount of Factor I in human plasma or serum samples.
Factor I (FI) is a negative regulatory protein of the complement system, and inhibits all pathways by cleaving activation components C4b and C3b. FI is a soluble protein, and circulates freely in the blood, though in an inactive state. Once FI is in the presence of a variety of co-factors it activates and inhibits complement activation. These co-factors include Factor H (only for C3b cleavage), MCP (CD46), CD35, and C4BP.
The MicroVue Factor I EIA measures the concentration of Factor I in serum or plasma. It uses a monoclonal antibody to Factor I, which is subsequently detected with an HRP-conjugated antibody that bind to another epitope of Factor I. This test, which provides a rapid, highly specific and quantitative procedure for measuring Factor I levels, is designed for investigations studying the role or status of complement pathway regulation in numerous research settings.
Product Specifications
|
Format
|
ELISA |
|
Assay Time
|
2 hours |
|
Test/kit
|
96 wells/plate |
|
Sample type
|
Serum/Plasma |
Ordering Information
| Catalog Number | Description |
|---|---|
|
A041
|
ELISA Kit, controls included |
