Phospho-IRF3 (Ser386) Rabbit Monoclonal Antibody
产品编号
|
产品名称
|
产品包装
|
产品价格
|
XY1594
|
Phospho-IRF3
(Ser386) Rabbit Monoclonal Antibody
|
50μl
|
618.00元
|
来源
|
用途
|
交叉反应性
|
分子量
|
Rabbit
|
WB, IF, ICC
|
H
|
47.0kDa
|
WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液,可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整):
WB
|
IP
|
IF
|
IHC
|
ICC
|
FC
|
ELISA
|
ChIP
|
1:1,000
|
-
|
1:50-1:200
|
-
|
1:50-1:200
|
-
|
-
|
-
|
抗体详细信息如下:
About this
Antibody
|
Name
|
Phospho-IRF3
(Ser386) Rabbit Monoclonal Antibody
|
Category
|
Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
|
Isotype
|
IgG
|
Purification
|
XYfinity
purification
|
About the
Immunogen
|
Immunogen
|
Recombinant
protein
|
Gene ID
|
3661(Human)
|
SwissProt
|
Q14653(Human)
|
Synonyms
|
-
|
Category
|
Immunology/Inflamation
|
Background
|
Interferon
regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel
DNA-binding factors that function as regulators of both type I interferon
(interferon-α and β) and
interferon-inducible genes. The two factors are structurally related,
particularly in their N-terminal regions, which confer DNA binding
specificity. In addition, both bind to the same sequence within the promoters
of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon
transcription, while IRF-2 binds to the same cis elements and represses IRF-1
action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic
manner in regulating cell growth; overexpression of the repressor IRF-2 leads
to cell transformation while concomitant overexpression of IRF-1 causes
reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding
proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3γ p48 and IFN consensus sequence-binding protein (ICSBP).
|
包装清单:
产品编号
|
产品名称
|
包装
|
XY1594
|
Phospho-IRF3
(Ser386) Rabbit Monoclonal Antibody
|
50μl
|
XY050
|
Western一抗稀释液
|
50ml
|
-
|
说明书
|
1份
|
保存条件:
Phospho-IRF3
(Ser386) Rabbit Monoclonal Antibody -20℃保存,Western一抗稀释液-20℃或4℃保存,一年有效。Western一抗稀释液优先推荐4℃保存,长期不使用可以考虑-20℃保存,但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验,请注意回收使用过的稀释抗体。回收的抗体通常至少可以重复使用5-10次。稀释后的抗体,包括已经使用过的稀释抗体,请4℃保存。
回收后重复使用的抗体,使用方法同新鲜稀释的抗体。如果在重复使用过程中发现抗体出现轻微混浊现象,可以10,000g离心1-3分钟,取上清用于后续检测。如果回收的抗体出现明显的絮状物或长霉长菌等情况,则可以考虑废弃该抗体。
提供的Western一抗稀释液也可以用于**荧光(IF)、**组化(IHC)、**细胞化学(ICC)等适当用途。如果希望获得*佳的检测效果,请考虑使用上述检测专用的一抗稀释液。
本产品**于专业人员的科学研究用,不得用于临床诊断或**,不得用于食品或药品,不得存放于普通住宅内。
为了您的**和健康,请穿实验服并戴一次性手套操作。
- 温馨提示:为规避购买风险,建议您在购买前务必确认供应商资质与产品质量。
- 免责申明:以上内容为注册会员自行发布,若信息的真实性、合法性存在争议,平台将会监督协助处理,欢迎举报