重组小鼠Lungkine/CXCL15 PP1002070-250μg

产品价格: ¥9920.00
产品型号:PP1002070-250μg
 牌:PERFEMIKER
公司名称:上海怡淼化学科技有限公司
  地:上海嘉定
发布时间:2018-09-06
浏览次数:
更多
立即询价 在线咨询

产品简介

名称:重组小鼠Lungkine/CXCL15

货号:PP1002070

规格:250μg

产品详细信息

名称:重组小鼠Lungkine/CXCL15

Accession:Q9WVL7

GeneID:20309

Unigene:Mm.64326.

Source:Escherichia coli.

Molecular Weight:Approximately 16.4 kDa, a single non-glycosylated polypeptide chain containing 142 amino acids.

AA Sequence:QELRCLCIQE HSEFIPLKLI KNIMVIFETI YCNRKEVIAV PKNGSMICLD PDAPWVKATV GPITNRFLPE DLKQKEFPPA MKLLYSVEHE KPLYLSFGRP ENKRIFPFPI RETSRHFADL AHNSDRNFLR DSSEVSLTGS DA

Purity:> 95 % by SDS-PAGE and HPLC analyses.

Biological Activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration of 20-100 ng/ml.

Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation:Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4, with 0.02 % Tween-20.

Endotoxin:Less than 1 EU/µg of rMuLungkine/CXCL15 as determined by LAL method.

Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Stability & Storage:Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Background:Mouse Lungkine/CXCL15, also named WECHE, is a member of the ELR motif-containing CXC chemokines. The cDNA of mouse Lungkine encodes a protein of 166 amino acids (aa) with a 25 aa predicted signal peptide and a 141 aa mature protein with an extremely long C terminal tail that protrudes beyond the chemokine fold. Mouse Lungkine shares 35% aa sequence identity with human ENA-78 and 31% identity with human IL-8. The gene for mouse Lungkine has been mapped to chromosome 5. By Northern blot and in situ hybridization, Lungkine transcripts are only specifically detected in the ***** and fetal lung, and its expression is up-regulated under inflammatory conditions. Lungkine protein is secreted into bronchoalveolar space and is involved in lung-specific neutrophils trafficking. Studies from Lungkine knock out mice suggests that Lungkine is an important mediator of neutrophil migration from the lung parenchyma into the airspace. Lungkine is also chemotactic for bone marrow progenitor cells and modulates hematopoietic cell differentiation

 

在线询价

您好,欢迎询价!我们将会尽快与您联系,谢谢!
  • *产品名称:
  • 采购数量:
  • 询价有效期:
  • *详细说明:
  •   100
  • *联系人:
  • *联系电话:
  • 附件: 附件支持RAR,JPG,PNG格式,大小在2M范围
验证码: 点击换一张
 
   温馨提示:为规避购买风险,建议您在购买前务必确认供应商资质与产品质量。

   免责申明:以上内容为注册会员自行发布,若信息的真实性、合法性存在争议,平台将会监督协助处理,欢迎举报