钙粘蛋白相关的神经受体2抗体 PCDA6

钙粘蛋白相关的神经受体2抗体

规格：1mg/1ml

英文名： PCDA6

别名： Cadherln-related neuronal receptor2; Cadherin related neuronal receptor 2; CNR 2; CNR2; CNRN 2; CNRN2; CNRS 2; CNRS2; CRNR 2; CRNR2; KIAA0345 like 8; PCDH alpha6; PCDHA 6; PCDHA-6; PCDA6_HUMA

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

**原：KLH conjugated synthetic peptide derived from human CNR-2

交叉反应：Human, Mouse, Rat, Cow, Horse,

细胞定位：细胞膜 分泌型蛋白

钙粘蛋白相关的神经受体2抗体产品介绍：background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins钙粘蛋白相关的神经受体2抗体 are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008] Function: Potential calcium-dependent cell-adhesion protein. May be involved in the 钙粘蛋白相关的神经受体2抗体establishment and maintenance of specific neuronal connections in the brain. Subunit: Contains 6 cadherin domains. Subcellular Location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted (Potential). Similarity: Contains 6 cadherin domains. Gene ID: 56142 Database links: Entrez Gene: 56142 Human Omim: 606312 Human SwissProt: Q9UN73 Human Unigene: 199343 Human Unigene: 570901 Human Unigene: 599714 Human Unigene: 621225 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

钙粘蛋白相关的神经受体2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：神经生物学  信号转导  细胞骨架  细胞膜蛋白  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid